Shakhtar Donetsk would be looking to make AS Roma the next team that leaves their home beaten like they did to Manchester City in the group stages, and they have the quality to achieve that.
They would also take some inspiration from the last time they both met in the 2010/2011 season when they outclassed the Italians 6-2 on aggregate thanks to a 2-3 win at the Stadio Olimpico.
Shakhtar won their last league game 5-0 at home to Odesa, a perfect preparation for this match.
Roma have had their problems on the road this season, but they would be looking to avoid a defeat in Kharkiv at all cost.
In the group stages, they proved a very tough nut to crack as they secured top spot in a group that had Chelsea.
Roma will be looking for at least a draw so that they would be under less pressure when the return leg is played in their home.
They head into this game off the back of three successive wins – the last of which was away from home.
Results of each team’s last 5 matches across all leagues and competitions
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