Colombia and Chile have been two of the most impressive teams in this competition so far apart from Brazil and now it means that one of them will be eliminated here.
Colombia won all of their group games beginning their campaign with a 2-0 victory over Argentina. They followed that up with subsequent wins over Paraguay and Qatar and what is perhaps even more impressive about them is that they have scored four goals and conceded none.
Their form so far has made them one of the favourites for this competition and they now have to eliminate the defending champions in order to reach the last 4.
Chile came into this competition in a poor run of form but they surprised many by winning their first two games before ultimately losing to Uruguay.
They now face their biggest test yet as they bid to retain the crown they have won in the past two editions of this competition.
Alexis Sanchez has been in fine form in this competition despite having an underwhelming full season at Manchester United. He will be key to them here plus this could be his last competition with the national team so fans will be expecting a solid performance from him and the rest of the Chile starting XI.
Bookmakers have priced Colombia up as slight favourites to come out on top in this game however the odds are tight and Chile are in with a real shout according to oddsmakers.
Goal markets point to a very tight game as under 2.5 goals is trading long odds-on prior to kick-off while Radamel Falcao and Duvan Zapata are vying for favourtism in the first goalscorer market.